3-(2,3-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one CAS 42220-80-4
| CAS No. | 42220-80-4 |
| Molecular Formula | C17H16O4 |
| Molecular Weight | 284.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-(2,3-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (CAS 42220-80-4) is a high-purity analytical reference standard with the molecular formula C17H16O4 and a molecular weight of 284.31 g/mol.
The molecular framework of 3-(2,3-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (C17H16O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures 3-(2,3-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H16O4 |
| Molecular Weight | 284.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
Related Dimethoxyphenyl Standards
- 2-(2,4-Dimethoxyphenyl)-2,3-dihydroquinazolin-4(1H)-one (CAS 108367-37-9)
- (E)-3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (CAS 151135-64-7)
- (E)-3-(3,4-dimethoxyphenyl)-1-(3-hydroxyphenyl)-2-propen-1-one (CAS 178445-80-2)
- 3-(3,4-Dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one (CAS 19152-36-4)
- (E)-3-(3,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one (CAS 66281-70-7)
- (Z)-2-(3,4-dimethoxyphenyl)-3-phenylacrylic acid (CAS 218932-62-8)
- 2-(3,4-Dimethoxyphenyl)-1,2,3,4-tetrahydroquinolin-4-amine (CAS 1923082-54-5)
- 3-(3,4-Dimethoxyphenyl)-5,7-dimethyl-2,3-dihydrobenzofuran (CAS 88467-28-1)
Recommended Standards
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- 3-(3-(Benzyloxy)-4-methoxyphenyl)acrylic acid (CAS 24807-37-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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