4-Chloro-N-methyl-3-(trifluoromethyl)aniline 42265-69-0 n-[4-chloro-3-(trifluoromethyl)phenyl]-n-methylamine CAS 42265-69-0
| CAS No. | 42265-69-0 |
| Molecular Formula | C8H7ClF3N |
| Molecular Weight | 209.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-N-methyl-3-(trifluoromethyl)aniline 42265-69-0 n-[4-chloro-3-(trifluoromethyl)phenyl]-n-methylamine (CAS 42265-69-0), a certified reference material (molecular formula C8H7ClF3N, MW 209.60 g/mol) for analytical method development and quality control.
The molecular framework of 4-Chloro-N-methyl-3-(trifluoromethyl)aniline 42265-69-0 n-[4-chloro-3-(trifluoromethyl)phenyl]-n-methylamine (C8H7ClF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Chloro-N-methyl-3-(trifluoromethyl)aniline 42265-69-0 n-[4-chloro-3-(trifluoromethyl)phenyl]-n-methylamine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7ClF3N |
| Molecular Weight | 209.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (4-chloro-2-(trifluoromethyl)phenyl)methanamine 1021051-94-4 4-Chloro-N-methyl-2-(trifluoromethyl)aniline (CAS 1021051-94-4)
- 2-Chloro-N-methyl-6-(trifluoromethyl)aniline (CAS 1152550-27-0)
- 4-Chloro-2-methyl-6-(trifluoromethyl)aniline (CAS 1240528-24-8)
- 4-Chloro-2-methyl-5-(trifluoromethyl)aniline (CAS 1379346-32-3)
- 3-Chloro-n-methyl-n-(trifluoromethyl)aniline (CAS 1420813-08-6)
- 2-(3-Chloro-4-fluorophenyl)-2,2-difluoroethan-1-amine (CAS 1553347-53-7)
- (2-Chloro-5-(trifluoromethyl)phenyl)methanamine (CAS 15996-78-8)
- 4-Chloro-3-Cyano-6-fluoro-2H-benzopyran (CAS 175205-57-9)
Recommended Standards
- 7-Fluoroquinoline-2-carbonyl chloride (CAS 497959-11-2)
- 2-Chloro-4-(3-fluoro-phenyl)-[1,3,5]triazine (CAS 1053658-51-7)
- 7-Chloro-5-fluoro-2-methylbenzofuran-3-carbonitrile (CAS 826990-59-4)
- 2-Chloro-4-(4-fluorophenyl)-1,3,5-triazine (CAS 1053658-58-4)
- 2-Methoxy-5-methylbenzaldehyde (CAS 7083-19-4)
- 5-Amino-8-(furan-2-yl)-3-(2-hydroxyethyl)thiazolo[5,4-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one (CAS 2246609-35-6)
- Dysprosium(III) i-propoxide (99.9%-Dy) (REO) (CAS 6742-68-3)
- 1-Isopropyl-2-methoxy-3-nitrobenzene (CAS 1000342-22-2)
- 1-Allyl-4-iodo-5-methyl-1H-pyrazole-3-carboxylic acid (CAS 1373247-63-2)
- 1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-thiol (CAS 5334-62-3)
- 2,4-Difluoro-6-hydroxybenzaldehyde (CAS 136516-64-8)
- 2-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1781636-40-5)
- 1-methyl-5-(phenoxymethyl)-1H-pyrazol-3-amine (CAS 1354704-34-9)
- [a-Glu](Side chain transposition)- Semaglutide (CAS CATO-C4X-2226111)
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