[2-Chloro-5-(trifluoromethyl)phenyl]ethylamine CAS 42266-12-6
| CAS No. | 42266-12-6 |
| Molecular Formula | C9H9ClF3N |
| Molecular Weight | 223.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
[2-Chloro-5-(trifluoromethyl)phenyl]ethylamine (CAS 42266-12-6), molecular formula C9H9ClF3N and molecular weight 223.62 g/mol, is a CATO reference standard with documented purity and traceability.
[2-Chloro-5-(trifluoromethyl)phenyl]ethylamine (C9H9ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H9ClF3N |
| Molecular Weight | 223.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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- 3-Chloro-2-methyl-6-nitroquinoxaline (CAS 101869-77-6)
- 5-Chloro-2-methyl-N-(2,2,2-trifluoroethyl)aniline (CAS 1021032-00-7)
- 3-Chloro-4-(4H-1,2,4-triazol-4-yl)benzoic acid (CAS 1060795-62-1)
- (R)-1-(4-Chloro-3-(trifluoromethyl)phenyl)ethanamine (CAS 1080064-51-2)
- 1-(4-Chloro-3-(trifluoromethyl)phenyl)ethanamine (CAS 1098069-36-3)
- 2-(2-Chloro-4-(trifluoromethyl)phenyl)ethan-1-amine (CAS 1160183-82-3)
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Recommended Standards
- (R)-1-(4-Chlorophenyl)-2,2,2-trifluoro-N-methylethan-1-amine (CAS 2381393-10-6)
- 1-(2-Chloro-3-(trifluoromethyl)phenyl)ethan-1-amine (CAS 72561-45-6)
- 4-Chloro-8-methyl-5-nitrocinnoline (CAS 1823849-83-7)
- 1-(2-Chloro-4-nitrophenyl)-1H-imidazole (CAS 862776-43-0)
- 2-Pyrrolidinoaniline (CAS 21627-58-7)
- α，α，α＇，α＇-Tetrabromo-m-xylene (CAS 36323-28-1)
- 2-Allyl-4-methyl-1-(pentyloxy)benzene (CAS 1443344-09-9)
- 3,4-Difluorothiophene-2-sulfonyl chloride (CAS 2657625-36-8)
- 2-((tert-butoxycarbonyl)(2-((2-((2,4-dimethylphenyl)thio)phenyl)amino)-2-oxoethyl)amino)ethyl methanesulfonate (CAS 2084805-38-7)
- 6-Methyl-2,6-diazaspiro[3.4]octane (CAS 135380-24-4)
- 6-chloro-n-(2-(pyridin-3-yl)ethyl)pyrimidin-4-amine (CAS 1248254-94-5)
- 1-(Benzyloxy)-4-chloropyrido[2,3-d]pyrimidin-2(1H)-one (CAS 1312356-10-7)
- 4-Ethyl-n-(2-furylmethyl)-1,3-benzothiazol-2-amine (CAS 1350988-95-2)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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