2-Chloro-N-(2-hydroxyethyl)propanamide CAS 42275-81-0
| CAS No. | 42275-81-0 |
| Molecular Formula | C5H10ClNO2 |
| Molecular Weight | 151.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-N-(2-hydroxyethyl)propanamide (C5H10ClNO2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
2-Chloro-N-(2-hydroxyethyl)propanamide (CAS 42275-81-0) is a high-purity analytical reference standard with the molecular formula C5H10ClNO2 and a molecular weight of 151.59 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Chloro-N-(2-hydroxyethyl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H10ClNO2 |
| Molecular Weight | 151.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- 6-Bromo-2-(3-fluorophenyl)-4H-chromen-4-one (CAS 213894-73-6)
- 2-Fluoro-3-(trifluoromethoxy)phenylacetonitrile (CAS 1159512-60-3)
- 1,3-Diethyl-1H-pyrazole-5-carbonyl chloride (CAS 126674-97-3)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
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