Pregabalin Impurity 29 CAS 4228-66-4
| CAS No. | 4228-66-4 |
| Molecular Formula | C9H8O5 |
| Molecular Weight | 196.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pregabalin Impurity 29.
CATO supplies Pregabalin Impurity 29 (CAS 4228-66-4), a pharmacopoeial impurity reference standard (molecular formula C9H8O5, MW 196.16 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Pregabalin Impurity 29 (C9H8O5) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 196.16 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Pregabalin Impurity 29 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8O5 |
| Molecular Weight | 196.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Pregabalin Standards
- Pregabalin EP Impurity D (CAS 89015-27-0)
- Pregabalin EP Impurity D (CAS 4118-51-8)
- Pregabalin Impurity 50 (CAS CATO-C4X-131250)
- Pregabalin Impurity 59 (CAS 53439-96-6)
- Pregabalin impurity 106 (CAS 871577-76-3)
- Pregabalin Impurity 86 (CAS CATO-C4X-131286)
- Pregabalin impurity 99 (CAS 1511511-44-6)
- Pregabalin Impurity 67 (CAS 1239856-83-7)
Recommended Standards
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- Epinephrine /Adrenaline Impurity 130 (CAS CATO-C4X-1849130)
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- Erlotinib Impurity 32 (CAS 236750-65-5)
- Ketoprofen Impurity 87 (CAS CATO-C4X-147187)
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- 4-(2-Chloro-6-nitrophenyl)butan-2-one (CAS 1338992-33-8)
- 1-(2,4-Dibromo-6-methoxyphenyl)ethanone (CAS 1423702-17-3)
- 6-(4-Fluorophenyl)-2,3-dihydroimidazo[2,1-b]thiazole (CAS 106465-78-5)
- 6-Amino-7-methyl-1,4-dihydroquinoxaline-2,3-dione (CAS 69904-14-9)
- PACAP-Related Peptide (PRP), rat (CAS 132769-35-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com