Carbazochrome Impurity N4 CAS 42372-66-7
| CAS No. | 42372-66-7 |
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Carbazochrome Impurity N4 (C10H12N4O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Carbazochrome Impurity N4 (CAS 42372-66-7, C10H12N4O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Carbazochrome Impurity N4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12N4O3 |
| Molecular Weight | 236.23 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 4 |
Related Carbazochrome Standards
- Carbazochrome (CAS 69-81-8)
- Carbazochrome Impurity 51 (CAS CATO-C4X-229151)
- Carbazochrome impurity 46 (CAS CATO-C4X-229146)
- Carbazochrome-d3 (CAS 69-81-8 (unlabelled))
- Carbazochrome Impurity 37 (CAS CATO-C4X-229137)
- Carbazochrome Impurity 11 (CAS CATO-C4X-229111)
- Carbazochrome Impurity 12 (CAS CATO-C4X-229112)
- Carbazochrome Impurity 6 (CAS CATO-C4X-22916)
Recommended Standards
- Piperazine Impurity 31 (CAS CATO-C4X-242731)
- Methyl (S)-2-amino-3-(5-fluoro-1H-indol-3-yl)propanoate (CAS 103022-24-8)
- (S)-1-(3,5-Difluorophenyl)ethyl methanesulfonate (CAS 1076195-98-6)
- n-(2-(Cyclopropylamino)-2-oxoethyl)-4-fluorobenzamide (CAS 1090350-93-8)
- Miglitol Impurity 7 (CAS 52541-36-3)
- Cefaclor Impurity 14 (CAS CATO-C4X-127014)
- m-Phenylenediamine Impurity 6 (CAS CATO-C4X-34286)
- 2-Bromo-6-[6-cyclopropyl-8-fluoro-1-oxoisoquinolin-2(1H)-yl]benzaldehyde (CAS 1642290-28-5)
- 2-Bromo-6-(bromomethyl)-5-(difluoromethyl)-3-iodopyridine (CAS 1805921-17-8)
- 2-Propenoic acid, 2-methyl-, 2-hydroxyethyl ester, polymer with butyl 2-propenoate, ethyl 2-propenoate and 2-propenoic acid (CAS 43127-25-9)
- Nickel(II) 1,4,8,11,15,18,22,25-octabutoxy-29H,31H-phthalocyanine (CAS 155773-71-0)
- 7-Chloro-N,N-dimethylquinolin-4-amine (CAS 22072-07-7)
- 1-(Pyridin-3-ylmethyl)piperidin-3-ol (CAS 130054-54-5)
- Semaglutide impurity 40 (CAS CATO-C4X-222640)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com