1-(5-Bromo-2-methoxybenzyl)piperazine CAS 423745-85-1
| CAS No. | 423745-85-1 |
| Molecular Formula | C12H17BrN2O |
| Molecular Weight | 285.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(5-Bromo-2-methoxybenzyl)piperazine (CAS 423745-85-1), molecular formula C12H17BrN2O and molecular weight 285.18 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Bromo-2-methoxybenzyl)piperazine (C12H17BrN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H17BrN2O |
| Molecular Weight | 285.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 1-Bromo-3-((1E,3E)-4-phenylbuta-1,3-dien-1-yl)benzene (CAS 174967-28-3)
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- 2-(4-Bromophenyl)-4,4,6-trimethyl-1,3-dioxane (CAS 171367-53-6)
- 2-(4-Bromobenzyl)hexanoic acid (CAS 857939-30-1)
- tert-Butyl (4-(dimethylphosphoryl)-3-fluoro-2-methoxyphenyl)carbamate (CAS 2903924-48-9)
- 7-Chloro-2,3-dihydro-1H-cyclopenta[b]quinoline-9-carboxylic acid (CAS 462066-99-5)
- (E)-(2-Chlorovinyl)benzene (CAS 4110-77-4)
- Lomefloxacin Impurity 10 （HCl） (CAS CATO-C4X-207310)
- 2-(1-Benzyl-1H-1,2,3-triazol-4-yl)-N-methylethan-1-amine (CAS 933719-82-5)
- CAS 685901-24-0 (CAS 685901-24-0)
- 3-(3-(Phenylthio)propyl)furan (CAS 89171-61-9)
- 3-(Tert-butoxycarbonyl)-5-fluoro-3-azabicyclo[3.1.1]Heptane-1-carboxylic acid (CAS 2344681-61-2)
- (1R,3R)-3-Aminocyclohexanecarboxylic Acid (CAS 933445-51-3)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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