4-((4-Chlorophenyl)sulfonyl)thiophene-3-carboxylic acid CAS 423769-77-1
| CAS No. | 423769-77-1 |
| Molecular Formula | C11H7ClO4S2 |
| Molecular Weight | 302.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-((4-Chlorophenyl)sulfonyl)thiophene-3-carboxylic acid (C11H7ClO4S2) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 4-((4-Chlorophenyl)sulfonyl)thiophene-3-carboxylic acid (CAS 423769-77-1), a certified reference material (molecular formula C11H7ClO4S2, MW 302.75 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-((4-Chlorophenyl)sulfonyl)thiophene-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H7ClO4S2 |
| Molecular Weight | 302.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- (2E)-3-(2-Chlorophenyl)-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1064057-84-6)
- (Z)-3-(4-chlorophenyl)-3-(4-ethoxyphenyl)acrylic acid (CAS 1226485-83-1)
- (2E)-3-(4-Chlorophenyl)-1-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 1345675-59-3)
- (2E)-1-(2-Chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1352347-01-3)
- (2E)-1-(2-Chlorophenyl)-3-(2,3-dimethoxyphenyl)prop-2-en-1-one (CAS 1354941-45-9)
- (2E)-1-(3-Chlorophenyl)-3-(2,5-dimethoxyphenyl)prop-2-en-1-one (CAS 1354941-49-3)
- Methyl 2-(4-chlorophenyl)-4-oxo-4-phenylbutanoate (CAS 1383253-45-9)
- (2E)-3-(3-Chlorophenyl)-1-(2,4-dimethoxyphenyl)prop-2-en-1-one (CAS 1482338-71-5)
Recommended Standards
- 3-(2-Chlorophenyl)-4,6-dimethoxy-2-methylbenzofuran (CAS 922140-93-0)
- 4-(4-Chlorophenyl)-2-(4-methylphenyl)-4-oxobutanoic acid (CAS 70596-90-6)
- 2-(4-Chlorophenyl)-4-(3-methylphenyl)-4-oxobutanoic acid (CAS 344281-24-9)
- Methyl 2-(3-chlorophenyl)-4-oxo-4-phenylbutanoate (CAS 344280-08-6)
- Ethyl 2-imino-10-methyl-5-oxo-1-propyl-2,5-dihydro-1H-dipyrido[1,2-a:2',3'-d]pyrimidine-3-carboxylate (CAS 500147-68-2)
- 1-Ethyl-2-methyl-1h-indole-3-sulfonamide (CAS 1375474-21-7)
- (R)-3-Amino-4-(2,4-dimethoxyphenyl)butanoic acid (CAS 1253790-20-3)
- 3-(3-Iodo-5-methylphenyl)pyridine (CAS 1214362-94-3)
- 5-Bromo-N-(1-methyl-1H-pyrazol-4-yl)thiophene-2-carboxamide (CAS 1241222-50-3)
- Benzenepropanoic acid, 2-hydroxy-.alpha.-oxo (CAS 1201-77-0)
- Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine (CAS 1344121-06-7)
- 2-(2-Oxopiperidin-1-yl)-2-phenylacetic acid (CAS 396129-93-4)
- 5-Bromo-N-(1-(diethylamino)-1-oxopropan-2-yl)thiophene-3-carboxamide (CAS 1218723-42-2)
- Neuropeptide GE (CAS 134748-04-2)
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