(E)-4-(4-Chlorophenyl)-2-oxobut-3-enoic acid CAS 42393-06-6
| CAS No. | 42393-06-6 |
| Molecular Formula | C10H7ClO3 |
| Molecular Weight | 210.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(E)-4-(4-Chlorophenyl)-2-oxobut-3-enoic acid (C10H7ClO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(E)-4-(4-Chlorophenyl)-2-oxobut-3-enoic acid (CAS 42393-06-6), molecular formula C10H7ClO3 and molecular weight 210.61 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-4-(4-Chlorophenyl)-2-oxobut-3-enoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7ClO3 |
| Molecular Weight | 210.61 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
Related E Standards
- (E)-4-(3-chlorophenyl)-2-oxobut-3-enoic acid (CAS 1244025-00-0)
- 4-Chlorophenyl sulfofluoridate (CAS 1535-33-7)
- 4-(3-Chlorophenyl)-4-oxo-2-butenoic Acid (CAS 191015-04-0)
- (E)-4-(4-chlorophenyl)-2-oxobut-3-enoic acid (CAS 33185-97-6)
- 3-(2-Chlorophenyl)dihydro-2,5-furandione (CAS 66041-30-3)
- 3-(4-Chlorophenyl)oxolane-2,5-dione (CAS 776-52-3)
- (E)-4-(4-chlorophenyl)-4-oxobut-2-enoic acid 3-(4-Chlorobenzoyl)acrylic acid 6269-33-6 (CAS 6269-33-6)
- [3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]methanol (CAS 1153452-00-6)
Recommended Standards
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- 2-(5-Chlorobenzofuran-2-yl)acetic acid (CAS 57329-17-6)
- 6-Chloro-4-hydroxy-3-methyl-2H-chromen-2-one (CAS 197504-51-1)
- n1-(Cyclopropylmethyl)-n1-propylethane-1,2-diamine (CAS 1156386-34-3)
- 5-Amino-2-mercaptothiazole-4-carboxamide (CAS 52868-63-0)
- (2-Bromo-5-chloro-4-methylphenyl)methanol (CAS 1849315-99-6)
- 3-Fluoro-4-((tetrahydro-2H-pyran-4-yl)oxy)benzoic acid (CAS 1402232-54-5)
- 2-Methyl-2-butenenitrile (CAS 4403-61-6)
- 5-Bromo-2,6-dioxohexahydropyrimidine-4-carboxylic acid (CAS 58668-21-6)
- Cis-3-amino-N-(3-amino-3-iminopropyl)cyclopentanecarboxamide sulfate (CAS 74984-58-0)
- 4-(4-Ethylbenzoyl)phenyl acetate (CAS 178860-08-7)
- Ethyl 4,5,6,7-tetrahydro-1H-pyrrolo[2,3-c]pyridine-2-carboxylate (CAS 104408-63-1)
- Tirzepatide Impurity 9 (CAS CATO-C4X-32409)
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