2-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide CAS 42458-71-9
| CAS No. | 42458-71-9 |
| Molecular Formula | C5H3ClF3N3OS |
| Molecular Weight | 245.61 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 42458-71-9) is a high-purity analytical reference standard with the molecular formula C5H3ClF3N3OS and a molecular weight of 245.61 g/mol.
Owing to an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 245.61 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5H3ClF3N3OS |
| Molecular Weight | 245.61 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-3,5-bis(difluoromethyl)-1H-pyrazol-1-yl)ethan-1-amine (CAS 1006469-07-3)
- 2-Chloro-4-((trifluoromethyl)sulfonyl)pyridine (CAS 2090223-43-9)
- Methyl 2-chloro-4-(trifluoromethyl)thiazole-5-carboxylate (CAS 72850-71-6)
- 4-Chloro-2-methoxy-5-nitro-benzoic acid methyl ester (CAS 109069-75-2)
- Methyl (4-chloro-2-nitrophenoxy)acetate (CAS 13212-52-7)
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Recommended Standards
- 4-(trifluoromethyl)pyridine-3-sulfonyl chloride (CAS 533932-27-3)
- 4-(Difluoromethyl)-6-fluoropyridine-2-sulfonyl chloride (CAS 1806781-54-3)
- 6-(Trifluoromethyl)pyridine-2-sulfonyl chloride (CAS 944900-24-7)
- 4-(Difluoromethyl)-6-fluoropyridine-3-sulfonyl chloride (CAS 1806771-18-5)
- (2R)-2-amino-3-cyclooctyl-propanoic acid (CAS 1689992-41-3)
- (3-(N,N-Diethylsulfamoyl)phenyl)boronic acid (CAS 871329-58-7)
- Tert-butyl 5-(hydroxymethyl)-2-azabicyclo[3.1.1]Heptane-2-carboxylate (CAS 2227205-64-1)
- 3-Amino-4-(dimethylamino)benzenesulfonamide (CAS 851175-91-2)
- (1s)-1-[4-(trifluoromethoxy)phenyl]ethan-1-ol (CAS 1108723-47-2)
- 6-Nitroquinoxalin-2(1H)-one (CAS 25652-34-0)
- 1,1,1-trifluoro-2-methyl-3-(4-{1H-pyrrolo[2,3-b]pyridin-3-yl}piperidin-1-yl)propan-2-ol (CAS 2430373-06-9)
- 2,3-Difluoro-6-methylbenzamide (CAS 1806332-05-7)
- N-((1-ethyl-1H-pyrazol-4-yl)methyl)-3-methylbutan-1-amine hydrochloride (CAS 1856096-75-7)
- D-[His]1-Semaglutide X TFA salt (CAS CATO-CPTD788634)
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