4'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one CAS 424792-51-8
| CAS No. | 424792-51-8 |
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one.
CATO supplies 4'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one (CAS 424792-51-8), a certified reference material (molecular formula C10H9NO2, MW 175.18 g/mol) for analytical method development and quality control.
The molecular framework of 4'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one (C10H9NO2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H9NO2 |
| Molecular Weight | 175.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 1 |
Related Hydroxyspiro Standards
- 5'-hydroxyspiro[cyclopropane-1,1'-isoindolin]-3'-one (CAS 1007455-36-8)
- 5'-Hydroxyspiro[cyclopropane-1,3'-indolin]-2'-one (CAS 1360938-08-4)
- methyl 2-hydroxyspiro[3.3]heptane-6-carboxylate (CAS 2620631-82-3)
- 9-hydroxyspiro[5.5]undecan-3-one (CAS 154464-88-7)
- 1-Hydroxyspiro[3.5]Nonane-1-carbonitrile (CAS 2104240-77-7)
- 7-Hydroxyspiro[3.5]nonane-2-carbonitrile (CAS 2851937-27-2)
- 5'-Hydroxyspiro[cyclobutane-1,3'-indolin]-2'-one (CAS 2770058-38-1)
- 2-hydroxyspiro[3.3]heptane-6-carboxylic acid (CAS 889944-59-6)
Recommended Standards
- 4-Hydroxy-8-methoxyquinoline (CAS 21269-34-1)
- 4-Methoxy-1H-indole-2-carbaldehyde (CAS 213682-04-3)
- 4-Hydroxy-8,8a-dihydroazeto[1,2-a]indol-2(1H)-one (CAS 205877-22-1)
- 4-Methoxy-1H-indole-7-carbaldehyde (CAS 389628-49-3)
- (1S,2S)-2-(Cyclopropylamino)cyclohexan-1-ol (CAS 189362-39-8)
- N-(2-Cyanophenyl)-2-(p-tolyl)acetamide (CAS 599162-84-2)
- Bromotrimethylammoniumbimame bromide, 95% (CAS 71418-45-6)
- Azilsartan Impurity 42 (CAS CATO-C4X-109642)
- 2-((Aminooxy)methyl)benzonitrile (CAS 854382-51-7)
- (2s,3r)-2,3-Diaminobutanoic acid dihydrochloride (CAS 215652-51-0)
- 2,6-Dioxohexahydropyrimidine-4-carbohydrazide (CAS 37458-09-6)
- 5-Aminopyrimidine-2,4,6(1H,3H,5H)-trione (CAS 118-78-5)
- (2-{[2-(Hexadecanoylsulfanyl)ethyl phosphonato]oxy}ethyl)trimethylazanium (CAS 60793-01-3)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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