N-(3-Iodophenyl)-2-nitrobenzenesulfonamide CAS 424805-03-8

Purity 97%+In StockPharmaceutical Standards
CAS No.424805-03-8
Molecular FormulaC12H9IN2O4S
Molecular Weight404.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(3-Iodophenyl)-2-nitrobenzenesulfonamide CAS 424805-03-8 chemical structure

Description

The occurrence of N-(3-Iodophenyl)-2-nitrobenzenesulfonamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(3-Iodophenyl)-2-nitrobenzenesulfonamide (CAS 424805-03-8), a certified reference material (molecular formula C12H9IN2O4S, MW 404.18 g/mol) for analytical method development and quality control.

The molecular framework of N-(3-Iodophenyl)-2-nitrobenzenesulfonamide (C12H9IN2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(3-Iodophenyl)-2-nitrobenzenesulfonamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H9IN2O4S
Molecular Weight404.18 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentI-containing
Nitrogen Atoms2
Sulfur Atoms1

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