2-Amino-7-(2-thienyl)-7,8-dihydroquinazolin-5(6H)-one CAS 424818-72-4
| CAS No. | 424818-72-4 |
| Molecular Formula | C12H11N3OS |
| Molecular Weight | 245.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-7-(2-thienyl)-7,8-dihydroquinazolin-5(6H)-one.
2-Amino-7-(2-thienyl)-7,8-dihydroquinazolin-5(6H)-one (CAS 424818-72-4), molecular formula C12H11N3OS and molecular weight 245.30 g/mol, is a CATO reference standard with documented purity and traceability.
2-Amino-7-(2-thienyl)-7,8-dihydroquinazolin-5(6H)-one (C12H11N3OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11N3OS |
| Molecular Weight | 245.30 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Amino Standards
- 6-(2-Amino-1,3-thiazol-4-yl)-1,2,3,4-tetrahydroquinolin-2-one (CAS 105316-79-8)
- 5-(2-Amino-5-methyl-1,3-thiazol-4-yl)-2,3-dihydro-1h-indol-2-one (CAS 105316-96-9)
- 3-Amino-4-[(2-methoxyethyl)amino]benzene-1-sulfonamide (CAS 1094243-21-6)
- 4-Amino-6-(1H-indol-4-yl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-44-3)
- 4-Amino-6-(1H-indol-5-yl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-68-1)
- 4-Amino-6-(1H-indol-6-yl)-1,6-dihydro-1,3,5-triazine-2-thiol (CAS 1142208-70-5)
- 3-(2-amino-4-methanesulfonylphenoxy)propan-1-ol (CAS 1154235-29-6)
- 5-amino-1-(4-methylpyridin-2-yl)-3-(methylsulfanyl)-1H-pyrazole-4-carbonitrile (CAS 1285256-32-7)
Recommended Standards
- 2-{1-amino-2-[(4-methoxyphenyl)sulfanyl]ethylidene}propanedinitrile (CAS 343375-45-1)
- 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)acetamide (CAS 73227-84-6)
- 2-{[2-(Aminocarbothioyl)hydrazino]carbonyl}cyclohexanecarboxylic acid (CAS 543695-36-9)
- 2-Hydrazinyl-4-(2-methylimidazo[1,2-a]pyridin-3-yl)thiazole (CAS 886503-45-3)
- 5-Amino-1-isopentylpyridin-2(1h)-one (CAS 1016698-42-2)
- 2-[(1-Piperidyl)methyl]aniline (CAS 19577-83-4)
- 2-((5-Imino-4,5-dihydro-1,3,4-thiadiazol-2-yl)thio)-N,N-dimethylacetamide (CAS 296879-33-9)
- tert-Butyl (3-(2-(methoxymethoxy)propan-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate (CAS 2577372-00-8)
- 2-Methoxy-5-(pyrrolidin-3-yl)pyridine (CAS 1008112-12-6)
- 4-Cyclopropylpiperidine hydrochloride (CAS 208245-61-8)
- 4,4'-Carbonylbis(isobenzofuran-1,3-dione) (CAS 13972-93-5)
- 2,6-Dimethyl-3-oxo-2,3-dihydropyridazine-4-carboxylic acid (CAS 857992-70-2)
- Iloperidone Stage -I Impurity (CAS 58113-30-7)
- Pancreatic Polypeptide (rat) (CAS 90419-12-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com