N-(5-Chloro-2-oxo-2,3-dihydrobenzofuran-3-yl)acetamide CAS 42493-04-9
| CAS No. | 42493-04-9 |
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(5-Chloro-2-oxo-2,3-dihydrobenzofuran-3-yl)acetamide (CAS 42493-04-9), molecular formula C10H8ClNO3 and molecular weight 225.63 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of N-(5-Chloro-2-oxo-2,3-dihydrobenzofuran-3-yl)acetamide (C10H8ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO3 |
| Molecular Weight | 225.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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- H-Glu-Gly-OH (CAS 13716-89-7)
- 3-Cyclohexyl-N-(2-(ethylamino)ethyl)propanamide hydrochloride (CAS 1581641-31-7)
- 3-ethoxy-4-[2-(4-morpholinyl)-2-oxoethoxy]-Benzaldehyde (CAS 98840-95-0)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
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