Roxithromycin EP Impurity I CAS 425365-66-8
| CAS No. | 425365-66-8 |
| Molecular Formula | C45H84N2O17 |
| Molecular Weight | 925.15 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 925.15 g/mol gives Roxithromycin EP Impurity I distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Roxithromycin EP Impurity I (CAS 425365-66-8), a pharmacopoeial impurity reference standard (molecular formula C45H84N2O17, MW 925.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C45H84N2O17, Roxithromycin EP Impurity I contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 925.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Roxithromycin EP Impurity I meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C45H84N2O17 |
| Molecular Weight | 925.15 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Roxithromycin Standards
- Roxithromycin Impurity 16 (CAS CATO-C4X-130316)
- Roxithromycin impurity 31 (CAS CATO-C4X-130331)
- Roxithromycin EP Impurity G (CAS 425365-64-6)
- Roxithromycin EP Impurity K (CAS CATO-C4X-130312)
- Roxithromycin Impurity 19 (CAS 1460313-73-8)
- Roxithromycin Impurity 20 (CAS 1460313-65-8)
- Roxithromycin impurity 27 (CAS CATO-C4X-130327)
- Roxithromycin Impurity 25 (CAS 1094780-37-6)
Recommended Standards
- OC-6-22-Iridium,tris[2-(4-methyl-5-phenyl-2-pyridinyl-κN)phenyl-κC] (CAS 2103257-53-8)
- 2,2,7,7-Tetra([1,1'-biphenyl]-4-yl)-2,7-dihydro-9,9'-spirobi[fluorene] (CAS 171408-93-8)
- Iridium, tris[3-(3-methyl-2-pyridinyl- N)[1,1’-biphenyl]-4-yl- C]- (CAS 861144-71-0)
- Mafodotin (CAS 863971-19-1)
- Dalilesen impurity 28 (CAS CATO-C4X-301028)
- Imatinib Impurity 69 (CAS 404577-34-0)
- Azelastine Impurity 68 (CAS CATO-C4X-139668)
- 1-(6-Methyl-5,6,7,8-tetrahydrocinnolin-3-yl)pyrrolidine-3-carboxylic acid (CAS 1713713-69-9)
- Ethyl 3-(4-aminopiperidin-1-yl)propanoate (CAS 174774-89-1)
- (S)-3-(Hydroxymethyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde (CAS 291507-78-3)
- Ertapenem impurity 49 (CAS 357154-27-9)
- 6-Bromoisoquinoline-3-carbonitrile (CAS 1780592-37-1)
- 2-(4-Fluorophenyl)-3-(pyridin-2-yl)propanoic acid (CAS 1017136-64-9)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com