2,2-Diphenyl-N-(4-(trifluoromethoxy)phenyl)acetamide CAS 425372-89-0
| CAS No. | 425372-89-0 |
| Molecular Formula | C21H16F3NO2 |
| Molecular Weight | 371.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 2,2-Diphenyl-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 425372-89-0), a certified reference material (molecular formula C21H16F3NO2, MW 371.35 g/mol) for analytical method development and quality control.
The molecular framework of 2,2-Diphenyl-N-(4-(trifluoromethoxy)phenyl)acetamide (C21H16F3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2,2-Diphenyl-N-(4-(trifluoromethoxy)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H16F3NO2 |
| Molecular Weight | 371.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Diphenyl Standards
- 1,1-Diphenyl-4-(pyrrolidin-1-yl)but-2-yn-1-yl dihydrogen phosphate (CAS 57248-89-2)
- 1-(5,7-Diphenyl-1,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)pyrrolidine-2,5-dione (CAS 171668-01-2)
- (S)-5,6-Diphenyl-N-((tetrahydrofuran-2-yl)methyl)furo[2,3-d]pyrimidin-4-amine (CAS 873305-35-2)
- 5,5-Diphenyl-3-((p-tolylamino)methyl)imidazolidine-2,4-dione (CAS 983-01-7)
- 1,3-Diphenyl-1-(3-phenyl-1,2,4-thiadiazol-5-yl)guanidine (CAS 61997-65-7)
- 4-(1,3-Diphenyl-4,5-dihydro-1H-pyrazol-5-yl)-N,N-diethylaniline (CAS 88439-40-1)
- 1-(5,7-Diphenyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)pyrrolidine-2,5-dione (CAS 836640-55-2)
- Ethyl 2,4-diphenyl-6-(pyrrolidin-1-yl)pyrimidine-5-carboxylate (CAS 823795-22-8)
Recommended Standards
- 2-([1,1'-Biphenyl]-4-yloxy)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 302551-12-8)
- 9-(b-D-Arabinofuranosyl)-N6-benzoyladenine (CAS 79896-97-2)
- (E)-2-(3-Cyano-4-(2-(7-hydroxy-2-oxo-2H-chromen-3-yl)vinyl)-5,5-dimethylfuran-2(5H)-ylidene)malononitrile (CAS 2123485-87-8)
- Ethyl (6-(benzylamino)-7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)glycinate (CAS 487035-65-4)
- [3-(propan-2-yl)piperidin-3-yl]methanol (CAS 1784390-15-3)
- 6-Morpholin-4-ylpyridazin-3-ol (CAS 27464-00-2)
- Methyl 2-{[2-({2-[(4-chlorophenyl)sulfanyl]ethyl}carbamoyl)ethyl]sulfanyl}benzoate (CAS 337923-23-6)
- 1,3-dihydroxypropan-2-yl 4-methylbenzenesulfonate (CAS 73684-56-7)
- 2-(3-Amino-4-methyl-1h-pyrazol-1-yl)propanoic acid (CAS 1245772-90-0)
- 3-Chlorothiophene-2-carbohydrazide (CAS 478483-31-7)
- 4-(2,6-Dimethyl-piperidin-1-ylmethyl)-phenylamine (CAS 328289-91-4)
- 4-Fluoroindolin-6-amine dihydrochloride (CAS 1823954-91-1)
- 6-(tert-Butoxy)-5-cyclopropoxynicotinaldehyde (CAS 1243323-21-8)
- Des-Gln24-Tirzepatide (CAS CATO-CPTD788949)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com