5-(trifluoromethyl)-1,2,4-triazin-3-amine CAS 425378-65-0

Description

The occurrence of 5-(trifluoromethyl)-1,2,4-triazin-3-amine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-(trifluoromethyl)-1,2,4-triazin-3-amine (CAS 425378-65-0), molecular formula C4H9F3N4 and molecular weight 170.14 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-(trifluoromethyl)-1,2,4-triazin-3-amine (C4H9F3N4) is characterized by fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-(trifluoromethyl)-1,2,4-triazin-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Why CATO?

• ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
• 130,000+ catalog items in stock, COA supplied with every batch
• Worldwide shipping with full export documentation (HS code guidance available)
• Technical support: +86 18665070610 / Nicole.chen@cato-chem.com