5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine CAS 425392-76-3
| CAS No. | 425392-76-3 |
| Molecular Formula | C5HBrClF3N2 |
| Molecular Weight | 261.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine is closely related to a nitrile group, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine (CAS 425392-76-3), molecular formula C5HBrClF3N2 and molecular weight 261.43 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine (C5HBrClF3N2) contains a nitrile group, fluorine/chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 261.43 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Bromo-4-chloro-6-(trifluoromethyl)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C5HBrClF3N2 |
| Molecular Weight | 261.43 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 5-Bromo-4-chloro-2-(trifluoromethyl)pyrimidine (CAS 1211586-58-1)
- 2-Bromo-5-chloro-4-(trifluoromethyl)pyrimidine (CAS 1257535-09-3)
- 4-Bromo-2-chloro-6-(trifluoromethyl)pyrimidine (CAS 1807115-57-6)
- 2-Bromo-3-chloro-5-(trifluoromethyl)pyrazine (CAS 1823377-50-9)
- 5-Bromo-2-chloro-4-(trifluoromethyl)pyrimidine (CAS 785777-92-6)
- 2-Bromo-4-chloro-6-nitrobenzonitrile (CAS 1082042-23-6)
- 5-Bromo-4-chloro-2-nitrobenzonitrile (CAS 1393442-14-2)
- 2-Bromo-3-chloro-5-nitrobenzonitrile (CAS 1426805-54-0)
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