4,5-Dichloro-2-methyl-6-(trifluoromethyl)pyrimidine CAS 425394-33-8
| CAS No. | 425394-33-8 |
| Molecular Formula | C6H3Cl2F3N2 |
| Molecular Weight | 231.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4,5-Dichloro-2-methyl-6-(trifluoromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
4,5-Dichloro-2-methyl-6-(trifluoromethyl)pyrimidine (CAS 425394-33-8), molecular formula C6H3Cl2F3N2 and molecular weight 231.00 g/mol, is a CATO reference standard with documented purity and traceability.
4,5-Dichloro-2-methyl-6-(trifluoromethyl)pyrimidine (C6H3Cl2F3N2) contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2F3N2 |
| Molecular Weight | 231.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-5-methyl-6-(trifluoromethyl)pyrimidine (CAS 1186423-90-4)
- 2,6-Dichloro-5-(trifluoromethyl)pyridin-3-amine (CAS 1196698-33-5)
- 1,3-Dichloro-2-(difluoromethoxy)-5-fluoro-benzene (CAS 1417567-25-9)
- 3,5-Dichloro-4-(trifluoromethyl)pyridin-2-amine (CAS 1446182-76-8)
- 4,6-Dichloro-2-(2,2,2-trifluoroethyl)pyrimidine (CAS 1465571-87-2)
- 1,3-Dichloro-5-(trifluoromethoxy)benzene (CAS 151276-08-3)
- 1,2-Dichloro-3-(trifluoromethoxy)benzene (CAS 151276-09-4)
- 1,2-Dichloro-4-(trifluoromethoxy)benzene (CAS 151276-10-7)
Recommended Standards
- 3,6-Dichloro-5-(trifluoromethyl)pyridin-2-amine (CAS 79456-29-4)
- 8-Bromo-1H-purine-2,6(3H,7H)-dione (CAS 10357-68-3)
- 2,6-Dichloro-3-(trifluoromethyl)phenol (CAS 393-00-0)
- (2-(Methoxycarbonyl)quinolin-8-yl)boronic acid (CAS 1242446-33-8)
- 1-(2-Methyl-6-(pyrrolidin-1-yl)pyridin-3-yl)propan-1-one (CAS 1355224-84-8)
- (1R,3r,5S)-9-Benzyl-9-azabicyclo[3.3.1]nonan-3-ol (CAS 70243-51-5)
- (S,S,S)-(+)-(3,5-Dioxa-4-phosphacyclohepta[2,1-a:3,4-a’]dinaphthalen-4-yl)bis(1-phenylethyl)amine (CAS 209482-27-9)
- (S)-2-Amino-3-(4-phosphonophenyl)propanoic acid (CAS 267236-68-0)
- (E)-3-(3,4-dimethoxyphenyl)-2-(4-(4-fluorophenyl)thiazol-2-yl)acrylonitrile (CAS 476671-88-2)
- 2,4-Difluorobenzene-1,3-Dicarbonitrile (CAS 73688-94-5)
- 5-Nitro-2-(trifluoromethoxy)benzaldehyde (CAS 160503-78-6)
- N-((1-((S)-2-Aminopropanoyl)piperidin-2-yl)methyl)acetamide (CAS 1354027-65-8)
- 3-Bromo-4-methyl-N-((3-methyl-1,2,4-oxadiazol-5-yl)methyl)benzamide (CAS 1424271-25-9)
- 59880-97-6 Chemotactic peptide F-Met-Leu-Phe L-Phenylalanine, N-(N-(N-formyl-L-methionyl)-L-leucyl)- N-Formyl-L-methionyl-L-leucyl-L-phenylalanine N-Formyl-Met-Leu-Phe N-Formylmethionine leucyl-phenylalanine fMLF fMLP (misnomer but widely used) (CAS 59880-97-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com