4-Chloro-5-cyano-6-difluoromethylpyrimidine CAS 425394-90-7
| CAS No. | 425394-90-7 |
| Molecular Formula | C6H2ClF2N3 |
| Molecular Weight | 189.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 189.55 g/mol gives 4-Chloro-5-cyano-6-difluoromethylpyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Chloro-5-cyano-6-difluoromethylpyrimidine (CAS 425394-90-7), molecular formula C6H2ClF2N3 and molecular weight 189.55 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C6H2ClF2N3, 4-Chloro-5-cyano-6-difluoromethylpyrimidine contains a nitrile group, fluorine/chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 189.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-5-cyano-6-difluoromethylpyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H2ClF2N3 |
| Molecular Weight | 189.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- 2-Chloro-5,7-difluoro-1,3-benzoxazole (CAS 1001185-79-0)
- 5-chloro-3-nitrobenzene-1,2-diol (CAS 116313-87-2)
- 2-chloro-5,6-difluorobenzo[d]oxazole (CAS 1233932-43-8)
- 3-Chloro-6-(difluoromethyl)pyrazine-2-carbonitrile (CAS 1257072-40-4)
- 2-Chloro-4,6-difluorobenzo[d]oxazole (CAS 1343514-56-6)
- 2-Chloro-6,7-difluorobenzoxazole (CAS 195737-22-5)
- 7-Chloro-4,6-difluoro-3H-imidazo[4,5-c]pyridine (CAS 405230-96-8)
- 2-Chloro-n-methyl-n-(2,2,2-trifluoroethyl)acetamide (CAS 1179829-40-3)
Recommended Standards
- 1006433-28-8 1-Methyl-4-nitro-1H-pyrazole-3-carbonyl chloride MFCD03421426 (CAS 1006433-28-8)
- 1-Methyl-4-nitro-1H-pyrazole-5-carbonyl chloride (CAS 1006962-20-4)
- 1-Methyl-5-nitro-1H-pyrazole-4-carbonyl chloride (CAS 121568-18-1)
- 2-(4-Nitro-1h-pyrazol-1-yl)acetyl chloride (CAS 1216050-54-2)
- (S)-4-Bromo-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)benzoic acid (CAS 2222743-02-2)
- 3-Methyl-2-(propan-2-yl)butane-1-thiol (CAS 110501-99-0)
- 1-(Methylsulfonyl)-4-(pyridin-2-yl)piperazine (CAS 496777-28-7)
- (3-Fluoro-2-propoxyphenyl)boronic acid (CAS 1010097-72-9)
- 3-(Trifluoromethoxy)isonicotinaldehyde (CAS 1361769-59-6)
- 3-Bromo-3-(4-fluorophenyl)propiophenone (CAS 898768-14-4)
- 2-(Benzylamino)-3-methylbutanamide (CAS 1248364-76-2)
- 2,6-Diallyl-4-vinyl-1,2,3,6-tetrahydropyridine (CAS 462068-10-6)
- 4-(4,5-Dichloro-6-oxo-1,6-dihydropyridazin-1-yl)benzene-1-sulfonic acid (CAS 33098-23-6)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com