6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol CAS 425702-95-0
| CAS No. | 425702-95-0 |
| Molecular Formula | C7H4F3N3O |
| Molecular Weight | 203.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol is closely related to an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol (CAS 425702-95-0), molecular formula C7H4F3N3O and molecular weight 203.12 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C7H4F3N3O, 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol contains an amide group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 203.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3-ol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H4F3N3O |
| Molecular Weight | 203.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Trifluoromethyl Standards
- 8-(trifluoromethyl)-9H-purin-2-amine (CAS 10179-89-2)
- 7-(Trifluoromethyl)imidazo[1,2-a]pyrimidin-5(8H)-one (CAS 1018125-95-5)
- 8-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one (CAS 1020039-20-6)
- 2-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidin-5(4H)-one (CAS 1239462-26-0)
- 4-(Trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-3-ol (CAS 1242267-84-0)
- 3-(Trifluoromethyl)benzo[d]isoxazol-5-ol (CAS 1260839-35-7)
- 6-(Trifluoromethyl)pyridine-2,4-dicarbaldehyde (CAS 1393550-38-3)
- 4-(Trifluoromethyl)pyridine-2,6-dicarbaldehyde (CAS 1393550-50-9)
Recommended Standards
- 5-Amino-6-oxo-3-(trifluoromethyl)-1,6-dihydropyridine-2-carbonitrile (CAS 951753-85-8)
- 6-(Trifluoromethyl)-1H-benzo[d][1,2,3]triazol-1-ol (CAS 26198-21-0)
- 5-(Trifluoromethyl)imidazo[1,5-b]pyridazin-3-ol (CAS 2803704-92-7)
- 6-(Trifluoromethyl)-9H-purin-2-amine (CAS 2993-20-6)
- Ethyl 5-(((tert-butoxycarbonyl)amino)methyl)-1,3,4-oxadiazole-2-carboxylate (CAS 164029-51-0)
- 2,3-Dimethyl-N-(piperidin-3-yl)butanamide (CAS 1339377-36-4)
- 4549-74-0 3-Methyl-1,3-pentadiene, (cis- and trans- mixture) MFCD00009277 (CAS 4549-74-0)
- 4-Chloro-2-(methylthio)-6-(piperazin-1-yl)pyrimidine hydrochloride (CAS 1261231-26-8)
- 3,4-Dibromo-1-methyl-pyrazole (CAS 89607-14-7)
- (R)-1-(2,4-dimethylphenyl)propan-1-amine hydrochloride (CAS 856563-03-6)
- Atrasentan Impurity 129 (CAS 1063835-99-3)
- 1,4-Bis(diphenylphosphino)butane-palladium(II) Chloride (CAS 29964-62-3)
- (3-(3,5-Dimethylisoxazol-4-yl)phenyl)boronic acid (CAS 1201799-16-7)
- Semaglutide Impurity 14(Discontinued,See CPTD788307 ) (CAS CATO-C4X-222614)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com