2-Chloro-5-iodo-3-nitropyridine CAS 426463-05-0
| CAS No. | 426463-05-0 |
| Molecular Formula | C5H2ClIN2O2 |
| Molecular Weight | 284.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-Chloro-5-iodo-3-nitropyridine (C5H2ClIN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine/iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-Chloro-5-iodo-3-nitropyridine (CAS 426463-05-0) is a high-purity analytical reference standard with the molecular formula C5H2ClIN2O2 and a molecular weight of 284.44 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C5H2ClIN2O2 |
| Molecular Weight | 284.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/I-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 2-Chloro-4-iodo-5-nitropyridine (CAS 1261882-76-1)
- 4-Chloro-2-iodo-6-nitropyridine (CAS 1805116-51-1)
- 5-Chloro-3-iodo-2-nitropyridine (CAS 1805626-98-5)
- 4-chloro-3-iodo-5-nitropyridine (CAS 1805643-82-6)
- 4-Chloro-5-iodo-2-nitropyridine (CAS 1805666-97-0)
- 5-Chloro-4-iodo-2-nitropyridine (CAS 1805666-99-2)
- 3-Chloro-4-iodo-5-nitropyridine (CAS 1807206-10-5)
- 4-Chloro-2-iodo-5-nitropyridine (CAS 1807206-13-8)
Recommended Standards
- 2-Chloro-3-iodo-5-nitropyridine (CAS 25391-60-0)
- 3-Chloro-2-iodo-5-nitropyridine (CAS 488713-29-7)
- 13-cis-Retinal (CAS 472-86-6)
- 3-Chloro-6-iodo-4-pyridazinecarboxylic acid (CAS 2241239-40-5)
- 4-(3,4-Dichlorophenyl)pyrimidine-5-carbaldehyde (CAS 1361707-08-5)
- 4-Bromo-2-ethyl-1-methoxybenzene (CAS 33839-11-1)
- 2-((2-Fluorobenzyl)thio)acetic acid (CAS 180044-55-7)
- tert-butyl 2-amino-5-azaspiro[3.4]octane-5-carboxylate (CAS 1363380-49-7)
- 4-Dimethylaminoazobenzene-4’-carboxylic Acid (CAS 6268-49-1)
- 4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(4-bromophenyl)-3-hydroxy-1-(3-methoxypropyl)-1H-pyrrol-2(5H)-one (CAS 498535-68-5)
- tert-Butyl (2-(3-amino-4-formylpyridin-2-yl)ethyl)carbamate (CAS 1393572-47-8)
- Z-Ser(tBu)-OSu (CAS 19460-97-0)
- 4-(3,5-Dimethyl-1,2-oxazole-4-carbonyl)morpholine (CAS 260354-82-3)
- [Glu]17-Liraglutide (CAS CATO-C4X-199236)
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