2-Fluoro-5-iodo-3-nitropyridine CAS 426463-16-3

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Fluoro-5-iodo-3-nitropyridine.

2-Fluoro-5-iodo-3-nitropyridine (CAS 426463-16-3) is a high-purity analytical reference standard with the molecular formula C5H2FIN2O2 and a molecular weight of 267.98 g/mol.

The molecular framework of 2-Fluoro-5-iodo-3-nitropyridine (C5H2FIN2O2) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Fluoro-5-iodo-3-nitropyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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