(2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine CAS 426844-76-0
| CAS No. | 426844-76-0 |
| Molecular Formula | C10H15FN2O2 |
| Molecular Weight | 214.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine (CAS 426844-76-0), molecular formula C10H15FN2O2 and molecular weight 214.24 g/mol, is a CATO reference standard with documented purity and traceability.
(2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine (C10H15FN2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2S,4S)-1-Boc-2-cyano-4-fluoropyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H15FN2O2 |
| Molecular Weight | 214.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (1S,3S,5R,6S)-3-hydroxy-8-methyl-8-azabicyclo[3.2.1]octan-6-yl acetate acetate (CAS 85644-59-3)
- (4,5-Dimethyl-6-oxo-1,6-dihydro-pyrimidin-2-ylsulfanyl)-acetic acid (CAS 499132-65-9)
- tert-Butyl (2R,4S)-2-cyano-4-fluoropyrrolidine-1-carboxylate (CAS 1932001-16-5)
- (4-Ethoxycarbonylthiazol-2-yl)guanidine (CAS 82982-26-1)
- (Heptafluoroisopropyl)benzene (CAS 378-34-7)
- beta-L-Aspartyl beta-naphthylamide (CAS 20283-77-6)
- N-Phenylmethyl-7-methyluric Acid (CAS 72816-95-6)
- Indoline-4-carboxylic acid (CAS 175647-03-7)
- (diphenylphosphoryl)methanesulfonamide (CAS 2455521-73-8)
- 2-Bromo-1,2,3,4-tetrahydronaphthalene (CAS 54753-94-5)
- Ethyl 3-(4-chlorophenyl)-3-methyloxirane-2-carboxylate (CAS 461437-55-8)
- CREBtide (CAS 149155-45-3)
- 1-Methyl-4-(morpholinosulfonyl)-1H-pyrrole-2-carboxylic acid (CAS 875163-97-6)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com