4-Androstene-3,17-dione D8 CAS 4273-45-4
| CAS No. | 4273-45-4 |
| Molecular Formula | - |
| Molecular Weight | 294.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Androstene-3,17-dione D8 (C19H18D8O2) contains deuterium isotope labeling, a steroid core, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-Androstene-3,17-dione D8 (CAS 4273-45-4) is a high-purity analytical reference standard with the molecular formula C19H18D8O2 and a molecular weight of 294.46 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18D8O2 |
| Molecular Weight | 294.46 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Androstene Standards
- ∆5-Androstene-3β,17β-diol-16,16,17-d3 (1.0mg/ml in Acetonitrile) (CAS 73609-45-7)
- 1-Androstene-3a,17ß-diol (CAS 38859-38-0)
- 4-Androstene-3,17-dione-13c3 (CAS 327048-86-2)
- 4-Androstene-3,17-Dione (CAS 63-05-8)
- 17-Methyl-4-androstene-3α,17α-diol (CAS 897950-19-5)
- 19-Nor-5-androstene-3β,17β-diol (1.0mg/ml in Acetonitrile) (CAS 25975-59-1)
- ∆1-Androstene-3α,17β-diol 17-Acetate (1.0mg/ml in Acetonitrile) (CAS 14291-94-2)
- 2-Androstene-1a,17-ß-diol (CAS 5846-70-8)
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