2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid CAS 42779-94-2

Purity 97%+In StockPharmaceutical Standards
CAS No.42779-94-2
Molecular FormulaC19H16FNO2
Molecular Weight309.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid CAS 42779-94-2 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 309.33 g/mol gives 2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid (CAS 42779-94-2), molecular formula C19H16FNO2 and molecular weight 309.33 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid (C19H16FNO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-(1-(4-Fluorophenyl)-2-methyl-5-phenyl-1H-pyrrol-3-yl)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC19H16FNO2
Molecular Weight309.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1969
Halogen ContentF-containing
Nitrogen Atoms1

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