4-(4-Fluorophenyl)morpholine CAS 4280-40-4
| CAS No. | 4280-40-4 |
| Molecular Formula | C10H12FNO |
| Molecular Weight | 181.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-(4-Fluorophenyl)morpholine (CAS 4280-40-4), molecular formula C10H12FNO and molecular weight 181.21 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 4-(4-Fluorophenyl)morpholine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 181.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-(4-Fluorophenyl)morpholine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FNO |
| Molecular Weight | 181.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)morpholine (CAS 1017396-52-9)
- 3-(2-Fluorophenyl)morpholine (CAS 1017418-51-7)
- 2-(2-Fluorophenyl)morpholine (CAS 1017480-65-7)
- 1-[(4-fluorophenyl)methyl]azetidin-3-ol (CAS 111043-49-3)
- 3-(3-Fluorophenyl)morpholine (CAS 1196551-89-9)
- (S)-3-(2-Fluorophenyl)morpholine (CAS 1212960-31-0)
- (R)-3-(2-Fluorophenyl)morpholine (CAS 1213337-38-2)
- 3-(3-Fluorophenyl)pyrrolidin-3-ol (CAS 1245648-01-4)
Recommended Standards
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