3-Bromo-5-ethoxy-4-(2-propynyloxy)benzaldehyde CAS 428474-72-0
| CAS No. | 428474-72-0 |
| Molecular Formula | C12H11BrO3 |
| Molecular Weight | 283.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
3-Bromo-5-ethoxy-4-(2-propynyloxy)benzaldehyde (CAS 428474-72-0), molecular formula C12H11BrO3 and molecular weight 283.12 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system, 3-Bromo-5-ethoxy-4-(2-propynyloxy)benzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 283.12 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11BrO3 |
| Molecular Weight | 283.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
Related Bromo Standards
- 1-(5-Bromo-2-fluoro-4-methylsulfonyl)-phenylhydrazine (CAS 1020722-17-1)
- Ethyl 3-bromo-5-methylimidazo[1,2-a]pyridine-2-carboxylate (CAS 1123167-64-5)
- Ethyl 3-bromo-5-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1132610-85-5)
- 6'-Bromo-1',2'-dihydrospiro[oxane-4,3'-pyrrolo[3,2-b]pyridine]-2'-one (CAS 1190862-19-1)
- Ethyl 5-bromo-4-methylbenzofuran-2-carboxylate (CAS 1192172-68-1)
- 6-Bromo-2-ethyl-8-methylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1215914-45-6)
- Ethyl 5-bromo-3-cyano-4,6-dimethylpicolinate (CAS 1221791-96-3)
- Methyl 6-bromo-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate (CAS 1254192-15-8)
Recommended Standards
- 3-Bromo-1-isopropyl-6-nitro-1H-indole (CAS 945556-87-6)
- 4-(2-Aminoethyl)-3-(3-bromophenyl)isoxazol-5(2H)-one (CAS 878208-97-0)
- 3-bromo-1-(oxan-2-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 2123463-60-3)
- 4-(4-Bromobenzoyl)-2-piperazinone (CAS 917562-11-9)
- 7-(Piperazin-1-yl)-1H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 1708013-52-8)
- 2-[3-cyclopropyl-6-ethyl-4-(trifluoromethyl)-1h-pyrazolo[3,4-b]pyridin-1-yl]acetic acid (CAS 1018125-49-9)
- tert-Butyl (5-chloro-6-cyanopyridin-3-yl)carbamate (CAS 1186637-78-4)
- 4-[(2,4,5-Trichlorophenoxy)methyl]piperidinehydrochloride (CAS 1219960-52-7)
- Methyl 3-(N-(methylsulfonyl)methylsulfonamido)propanoate (CAS 1207604-92-9)
- N-(4-Aminophenyl)-2-propoxybenzamide (CAS 1020054-03-8)
- 2-(4-Acetyl-3-fluorophenyl)acetic acid (CAS 2007909-82-0)
- 2-(((3-Bromothiophen-2-yl)methyl)amino)cyclohexan-1-ol (CAS 1247639-08-2)
- 7-chlorobenzofuran-3-one (CAS 3260-94-4)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com