3-Chloro-5-ethoxy-4-isopropoxybenzaldehyde CAS 428501-78-4
| CAS No. | 428501-78-4 |
| Molecular Formula | C12H15ClO3 |
| Molecular Weight | 242.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Chloro-5-ethoxy-4-isopropoxybenzaldehyde meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
3-Chloro-5-ethoxy-4-isopropoxybenzaldehyde (CAS 428501-78-4) is a high-purity analytical reference standard with the molecular formula C12H15ClO3 and a molecular weight of 242.70 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 3-Chloro-5-ethoxy-4-isopropoxybenzaldehyde is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 242.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H15ClO3 |
| Molecular Weight | 242.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
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Recommended Standards
- 3-Chloro-2-(p-tolyl)-2H-indazole (CAS 70704-41-5)
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- 2-[(2,6-Dichlorophenyl)sulfanyl]-N-[2-(phenylsulfanyl)ethyl]propanamide (CAS 337923-55-4)
- 6-Chloro-5-fluoro-3-pyridinecarbonyl chloride (CAS 78686-85-8)
- 4-(2,2-Diphenylethyl)piperazin-1-amine (CAS 39139-55-4)
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- Methyl pyrrolo[1,2-c]pyrimidine-3-carboxylate (CAS 58298-71-8)
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