1-(2-Chloroquinolin-4-yl)ethan-1-one CAS 4295-02-7
| CAS No. | 4295-02-7 |
| Molecular Formula | C11H8ClNO |
| Molecular Weight | 205.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 1-(2-Chloroquinolin-4-yl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
1-(2-Chloroquinolin-4-yl)ethan-1-one (CAS 4295-02-7), molecular formula C11H8ClNO and molecular weight 205.64 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Chloroquinolin-4-yl)ethan-1-one (C11H8ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H8ClNO |
| Molecular Weight | 205.64 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloroquinolin Standards
- 1-(4-Chloroquinolin-8-yl)ethanone (CAS 114935-94-3)
- 1-(2-Chloroquinolin-6-yl)ethanone (CAS 1253972-47-2)
- 1-(2-Chloroquinolin-8-yl)ethan-1-one (CAS 1453798-46-3)
- 1-(2-Chloroquinolin-7-yl)ethanone (CAS 1509899-45-9)
- 1-(3-Chloroquinolin-6-yl)ethan-1-one (CAS 1635407-48-5)
- 1-(3-Chloroquinolin-7-yl)ethan-1-one (CAS 1884155-74-1)
- 1-(2-Chloroquinolin-3-yl)ethanone (CAS 94741-41-0)
- 1-(4-Chloroquinolin-6-yl)ethanone (CAS 859962-03-1)
Recommended Standards
- 1-(3-Chloro-5-formylphenyl)cyclopropane-1-carbonitrile (CAS 2830620-98-7)
- 1-(2-Chloroacetamido)cyclopentane-1-carboxylic acid (CAS 90153-48-3)
- 1-(3-Chloroisoquinolin-1-yl)ethan-1-one (CAS 342622-21-3)
- 1-(1-Chloro-8-isoquinolyl)ethanone (CAS 2749401-99-6)
- 4-Amino-2-(difluoromethyl)-5-(trifluoromethyl)nicotinic acid (CAS 1806844-97-2)
- 4-((2-Hydroxyphenyl)amino)naphthalene-1,2-dione (CAS 175136-53-5)
- 2-((4-Ethyl-5-methyl-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 886498-62-0)
- 3-(3-(Trifluoromethyl)phenyl)-1,2,4-oxadiazole (CAS 16013-12-0)
- 1-(Chloromethyl)-1-isopentylcyclopropane (CAS 1487258-00-3)
- tert-Butyl (3S,4R)-3-methyl-1,6-diazaspiro[3.4]octane-1-carboxylate (CAS 2488950-47-4)
- 3-Iodo-4-(Trifluoromethoxy)benzamide (CAS 1365968-75-7)
- 3-{[(4-chlorophenyl)sulfanyl]methyl}-5-phenyl-1,2-oxazole (CAS 478067-78-6)
- 1-(CHLOROMETHYL)-2,5-DIFLUORO-4-METHYLBENZENE (CAS 1499128-34-5)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com