2-Chloro-5-hydroxynicotinic acid CAS 42959-40-0
| CAS No. | 42959-40-0 |
| Molecular Formula | C6H4ClNO3 |
| Molecular Weight | 173.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Chloro-5-hydroxynicotinic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 2-Chloro-5-hydroxynicotinic acid (CAS 42959-40-0), a certified reference material (molecular formula C6H4ClNO3, MW 173.55 g/mol) for analytical method development and quality control.
2-Chloro-5-hydroxynicotinic acid (C6H4ClNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C6H4ClNO3 |
| Molecular Weight | 173.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- 2-Chloro-3-nitrophenol (CAS 603-84-9)
- 2-Chloro-5-nitrophenol (CAS 619-10-3)
- 2-Chloro-3,6-difluorobenzonitrile (CAS 886501-33-3)
- 2-Chloro-6-nitrophenol (CAS 603-86-1)
- (4,6-Dihydroxy-5-(3-(triethoxysilyl)propyl)-1,3-phenylene)bis(phenylmethanone) (CAS 166255-23-8)
- 2-(2-Butylamino)ethanol (CAS 35265-04-4)
- 1-Bromo-4-ethoxy-1,1-difluorobut-3-en-2-one (CAS 1186025-41-1)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-2-sulfonyl chloride (CAS 1443980-37-7)
- 2-Chloro-5-(4-(3-nitrophenyl)buta-1,3-dien-1-yl)benzene-1-sulfonyl fluoride (CAS 31368-38-4)
- 3-Benzyl-7-chloro-5-phenyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (CAS 433922-12-4)
- 10H-Phenoxazine-3-carbonitrile (CAS 349453-39-0)
- 4-Allyl-2-methoxyphenyl Methanesulfonate (CAS 91971-63-0)
- N-(2-Methoxybenzyl)-1-naphthalenamine (CAS 861225-65-2)
- Peptide Impurity 15 (CAS 1227750-69-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com