2-Amino-5-(2-bromo-5-ethoxybenzylidene)thiazol-4(5H)-one CAS 430464-20-3
| CAS No. | 430464-20-3 |
| Molecular Formula | C12H11BrN2O2S |
| Molecular Weight | 327.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Amino-5-(2-bromo-5-ethoxybenzylidene)thiazol-4(5H)-one (C12H11BrN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
2-Amino-5-(2-bromo-5-ethoxybenzylidene)thiazol-4(5H)-one (CAS 430464-20-3) is a high-purity analytical reference standard with the molecular formula C12H11BrN2O2S and a molecular weight of 327.20 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Amino-5-(2-bromo-5-ethoxybenzylidene)thiazol-4(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11BrN2O2S |
| Molecular Weight | 327.20 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Amino Standards
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Recommended Standards
- 1-(4-Bromobenzenesulfonyl)-3-cyclopropyl-1H-pyrazole (CAS 956977-35-8)
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- tert-Butyl (6-iodohexyl)carbamate (CAS 172846-36-5)
- 2-Methoxy-4-methyl-5-(1-methylpyrrolidin-2-yl)pyridine (CAS 1352506-47-8)
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- 8-Bromo-3-methyl-1,2,3,4-tetrahydroquinoline (CAS 1017139-11-5)
- Spirodiclofen-enol (CAS 148476-22-6)
- Ethyl 3-oxo-2,3-dihydro-1H-pyrazolo[4,3-c]quinoline-8-carboxylate (CAS 1015572-07-2)
- 1-[1-(fluoromethyl)cyclopropyl]methanamine (CAS 1550947-28-8)
- (3R,4R)-tert-Butyl 3,4-bis(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 895245-32-6)
- 2-(3-Fluoro-5-(trifluoromethyl)phenyl)-2-oxoacetic acid (CAS 1443340-27-9)
- Semaglutide Impurity 124 (CAS CATO-C4X-2226124)
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