Terfenadine EP Impurity A CAS 43076-30-8
| CAS No. | 43076-30-8 |
| Molecular Formula | C32H39NO2 |
| Molecular Weight | 469.66 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Terfenadine EP Impurity A (CAS 43076-30-8, C32H39NO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Terfenadine EP Impurity A (C32H39NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 469.66 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Terfenadine EP Impurity A under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C32H39NO2 |
| Molecular Weight | 469.66 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 1 |
Related Terfenadine Standards
Recommended Standards
- Glycocholic-2,2,4,4-d4 Acid (CAS 1201918-15-1)
- Ebastine (CAS 90729-43-4)
- Bilastine-d6 (CAS 1215358-58-9)
- 6,7-Dichloro-4-(4-chlorophenyl)-2-[4-(trifluoromethyl)phenyl]-1,2-dihydrophthalazin-1-one (CAS 478066-04-5)
- Resmetirom Impurity 31 (CAS CATO-C4X-291231)
- Furosemide Impurity 59 (CAS 518336-22-6)
- Tranexamic Acid EP Impurity D (CAS 56-91-7)
- 3-Chloro-4-(trifluoromethoxy)benzoyl cyanide (CAS 80277-44-7)
- 4-(Difluoromethyl)-6-fluoro-2-methoxypyridin-3-ol (CAS 1806996-10-0)
- 2-(Quinolin-2-yl)acetonitrile (CAS 14068-28-1)
- 2-(4-Methyl-2-phenyl-1H-imidazol-5-yl)acetonitrile hydrochloride (CAS 103091-50-5)
- 1-Cyanopropane-2-sulfonyl chloride (CAS 2089256-19-7)
- 2-(4-Aminophenyl)-N,N-dimethylacetamide (CAS 81709-36-6)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com