((1S,2S,5R)-2-Isopropyl-5-methylcyclohexyl)diphenylphosphine CAS 43077-29-8

Purity 97%+In StockPharmaceutical Standards
CAS No.43077-29-8
Molecular FormulaC22H29P
Molecular Weight324.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

((1S,2S,5R)-2-Isopropyl-5-methylcyclohexyl)diphenylphosphine CAS 43077-29-8 chemical structure

Description

((1S,2S,5R)-2-Isopropyl-5-methylcyclohexyl)diphenylphosphine (CAS 43077-29-8), molecular formula C22H29P and molecular weight 324.44 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of ((1S,2S,5R)-2-Isopropyl-5-methylcyclohexyl)diphenylphosphine (C22H29P) is characterized by organophosphorus functionality, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H29P
Molecular Weight324.44 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1969

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