3-Bromo-1,1,1-trifluoropropan-2-ol CAS 431-34-5
| CAS No. | 431-34-5 |
| Molecular Formula | C3H4BrF3O |
| Molecular Weight | 192.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-Bromo-1,1,1-trifluoropropan-2-ol is closely related to a hydroxyl group, an ether linkage, fluorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 3-Bromo-1,1,1-trifluoropropan-2-ol (CAS 431-34-5), a certified reference material (molecular formula C3H4BrF3O, MW 192.96 g/mol) for analytical method development and quality control.
The molecular framework of 3-Bromo-1,1,1-trifluoropropan-2-ol (C3H4BrF3O) is characterized by a hydroxyl group, an ether linkage, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Bromo-1,1,1-trifluoropropan-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C3H4BrF3O |
| Molecular Weight | 192.96 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F/Br-containing |
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