5-Nitro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one CAS 43103-81-7
| CAS No. | 43103-81-7 |
| Molecular Formula | C7H5N3O3 |
| Molecular Weight | 179.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Nitro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (CAS 43103-81-7), molecular formula C7H5N3O3 and molecular weight 179.13 g/mol, is a CATO reference standard with documented purity and traceability.
5-Nitro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one (C7H5N3O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 5-Nitro-1H-pyrrolo[2,3-b]pyridin-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H5N3O3 |
| Molecular Weight | 179.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Nitrogen Atoms | 3 |
Related Nitro Standards
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- 3-Nitro-1H-pyrrolo[3,2-b]pyridin-5-ol (CAS 1190311-92-2)
- 3-Nitro-1H-pyrrolo[3,2-c]pyridin-4-ol (CAS 1190314-28-3)
- 4-Nitro-1H-pyrrolo[2,3-b]pyridin-5-ol (CAS 1190318-01-4)
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- N-ethyl-N-methylmethanesulfonamide (CAS 55790-96-0)
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