1-(2-(1H-indol-3-yl)ethyl)-3-(o-tolyl)thiourea CAS 431066-73-8

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2-(1H-indol-3-yl)ethyl)-3-(o-tolyl)thiourea.

1-(2-(1H-indol-3-yl)ethyl)-3-(o-tolyl)thiourea (CAS 431066-73-8), molecular formula C18H19N3S and molecular weight 309.43 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 1-(2-(1H-indol-3-yl)ethyl)-3-(o-tolyl)thiourea (C18H19N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 309.43 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(2-(1H-indol-3-yl)ethyl)-3-(o-tolyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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