n2-(4-Fluorophenyl)-n4-(furan-2-ylmethyl)quinazoline-2,4-diamine CAS 431072-56-9
| CAS No. | 431072-56-9 |
| Molecular Formula | C19H15FN4O |
| Molecular Weight | 334.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
n2-(4-Fluorophenyl)-n4-(furan-2-ylmethyl)quinazoline-2,4-diamine (CAS 431072-56-9) is a high-purity analytical reference standard with the molecular formula C19H15FN4O and a molecular weight of 334.35 g/mol.
The molecular framework of n2-(4-Fluorophenyl)-n4-(furan-2-ylmethyl)quinazoline-2,4-diamine (C19H15FN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H15FN4O |
| Molecular Weight | 334.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
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- 3-(4-Fluorophenyl)-3-(2-hydroxy-4-methylphenyl)isobenzofuran-1(3H)-one (CAS 148238-44-2)
- 3-(4-Fluorophenyl)-3-(4-hydroxy-2-methylphenyl)isobenzofuran-1(3H)-one (CAS 148238-45-3)
- (5E)-3-(4-Fluorophenyl)-5-{[(4-fluorophenyl)amino]methylidene}-4-oxo-1,3-thiazolidin-1-ium-1-olate (CAS 338753-14-3)
- 1-[(4-Fluorophenyl)methyl]-6-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile (CAS 252060-11-0)
- Ethyl 2-((5-(4-fluorophenyl)-3,5-dihydro-1H-thieno[3,4-c]pyrrol-4-yl)amino)-2-oxoacetate (CAS 1172080-99-7)
Recommended Standards
- N-(Benzo[d][1,3]dioxol-5-ylmethyl)-2-((6-methyl-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)thio)acetamide (CAS 460726-71-0)
- O-Demethylchelerythrine (CAS 66804-20-4)
- N-(4-(N-(benzo[d][1,3]dioxol-5-yl)sulfamoyl)phenyl)acetamide (CAS 333747-86-7)
- Raltegravir EP Impurity A (CAS 518048-03-8)
- 4-Chloro-3-(3-methyl-2,5-dioxo-3-phenylpyrrolidin-1-yl)benzenesulfonamide (CAS 30279-22-2)
- 2,2',5,6'-Tetrabromodiphenyl Ether (CAS 446254-25-7)
- 4-methyl-1H,2H,3H,4H-pyrido[2,3-b]pyrazin-2-one (CAS 1314974-86-1)
- 2-Chloro-N-[2-(4-chlorophenyl)ethyl]acetamide (CAS 3840-66-2)
- 3-((Furan-2-ylmethyl)amino)-4-oxo-4-(phenylamino)butanoic acid (CAS 1022919-76-1)
- 3-(5-(4-Chlorophenyl)furan-2-yl)-1-(piperidin-1-yl)propan-1-one (CAS 853312-23-9)
- (2-Morpholinothiazol-4-yl)methanamine (CAS 1023811-09-7)
- N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dimethoxybenzamide (CAS 166115-70-4)
- 7-Methyl-2-naphthonitrile (CAS 38879-96-8)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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