Zopiclone EP Impurity A CAS 43200-96-0
| CAS No. | 43200-96-0 |
| Molecular Formula | C17H17ClN6O4 |
| Molecular Weight | 404.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Zopiclone EP Impurity A (CAS 43200-96-0), a certified reference material (molecular formula C17H17ClN6O4, MW 404.81 g/mol) for analytical method development and quality control.
The molecular framework of Zopiclone EP Impurity A (C17H17ClN6O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H17ClN6O4 |
| Molecular Weight | 404.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Zopiclone Standards
Recommended Standards
- Eszopiclone EP Impurity A (CAS 151851-70-6)
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- 2-[(2-Chloro-6-fluorophenyl)methyl]-4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1H,2H,3H,5H,6H,7H,8H-pyrido[1,2-c]pyrimidine-1,3-dione (CAS 1775444-02-4)
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- 3-(4-Chlorophenyl)-1,2,4-thiadiazole-5-carboxylic acid (CAS 187999-26-4)
- 2-Cyclopropyl-2-(pyrrolidin-1-yl)acetic acid (CAS 1247438-75-0)
- 5-aminohexan-1-ol hydrochloride (CAS 1820747-48-5)
- 2-Amino-6-methoxybenzothiazole (CAS 1747-60-0)
- 4-Amino-3'-(benzyloxy)[1,1'-biphenyl]-3-carboxylic acid (CAS 893738-17-5)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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