5-Bromothiophen-2(3H)-one CAS 43225-51-0
| CAS No. | 43225-51-0 |
| Molecular Formula | C4H3BrOS |
| Molecular Weight | 179.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Bromothiophen-2(3H)-one (CAS 43225-51-0) is a high-purity analytical reference standard with the molecular formula C4H3BrOS and a molecular weight of 179.04 g/mol.
Owing to sulfur-containing functionality, a hydroxyl group, an ether linkage, bromine substitution, 5-Bromothiophen-2(3H)-one is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 179.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Bromothiophen-2(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H3BrOS |
| Molecular Weight | 179.04 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1969 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromothiophen Standards
- 5-Bromothiophen-2-ol (CAS 1313392-39-0)
- 4-Bromothiophen-3-ol (CAS 1414637-78-7)
- 5-Bromothiophen-2(5H)-one (CAS 17019-33-9)
- 5-Bromothiophen-3-ol (CAS 1895301-60-6)
- 2-Bromothiophen-3-amine (CAS 106944-13-2)
- 5-Bromothiophen-2-amine (CAS 1159882-51-5)
- 4-Bromothiophen-2-amine (CAS 1163729-45-0)
- 4-Bromothiophen-3-amine (CAS 161833-43-8)
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