5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid CAS 432499-63-3
| CAS No. | 432499-63-3 |
| Molecular Formula | C22H14ClNO4S2 |
| Molecular Weight | 455.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid (CAS 432499-63-3), a certified reference material (molecular formula C22H14ClNO4S2, MW 455.93 g/mol) for analytical method development and quality control.
The molecular framework of 5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid (C22H14ClNO4S2) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(5-((3-Benzyl-4-oxo-2-thioxothiazolidin-5-ylidene)methyl)furan-2-yl)-2-chlorobenzoic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H14ClNO4S2 |
| Molecular Weight | 455.93 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Recommended Standards
- 3-[(2H-1,3-Benzodioxol-5-yl)methyl]-5-{[5-(2-chlorophenyl)furan-2-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one (CAS 691881-87-5)
- Ethyl 3-(N-(5-chloro-2,4-dimethoxyphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932464-60-3)
- 2-(3-Chloro-4-methoxyphenyl)-1-(4-{[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperidin-1-yl)ethan-1-one (CAS 1775482-42-2)
- Elvitegravir-d6 (Major) (CAS CATO-C4X-21821)
- 2-methoxybutanenitrile (CAS 253317-26-9)
- Ruthenium(2+), bis(acetonitrile)bis[1,3-dihydro-1-(2-pyridinyl-κN)-3-(2,4,6-trimethylphenyl)-2H-imidazol-2-ylidene-κC]-, (OC-6-33)-, hexafluorophosphate(1-) (1:2) (CAS 2088512-45-0)
- 1-Ethyl-2-methyl-6-(trifluoromethyl)quinolin-4(1H)-one (CAS 1209277-82-6)
- 2-(Triisopropylsilyl)oxazole-5-boronic Acid Pinacol Ester (CAS 1186127-11-6)
- N-(2-(1H-pyrazol-3-yl)benzofuran-3-yl)acetamide (CAS 1401785-89-4)
- 3-(2,6-Difluorophenyl)-1h-1,2,4-triazol-5-amine (CAS 1016713-07-7)
- 2-Chloroethyl 5-(1,3-dioxolan-2-yl)-2-thienyl ketone (CAS 898772-41-3)
- 4-Chloropyridine-2,6-dicarbonyl dichloride (CAS 71022-75-8)
- 1-(Cyclopent-2-en-1-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione (CAS 138191-89-6)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com