8-Chloro-2-(2,4-dimethylphenyl)quinoline-4-carboxylic acid CAS 433249-00-4
| CAS No. | 433249-00-4 |
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 8-Chloro-2-(2,4-dimethylphenyl)quinoline-4-carboxylic acid (CAS 433249-00-4), a certified reference material (molecular formula C18H14ClNO2, MW 311.76 g/mol) for analytical method development and quality control.
8-Chloro-2-(2,4-dimethylphenyl)quinoline-4-carboxylic acid (C18H14ClNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 8-Chloro-2-(2,4-dimethylphenyl)quinoline-4-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14ClNO2 |
| Molecular Weight | 311.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Ethyl 2-chloro-4-phenylquinoline-3-carboxylate (CAS 101606-42-2)
- 2-Chloro-N-(4-(2-morpholinoacetamido)phenyl)acetamide (CAS 1049872-60-7)
- 4-Chloro-6,7-bis(2-methoxyethoxy)quinoline (CAS 1137579-56-6)
- 3-Acetyl-6-chloro-4-(4-methylphenyl)quinolin-2(1H)-one (CAS 1283108-80-4)
- Ethyl 6-chloro-4-phenylquinoline-3-carboxylate (CAS 128832-35-9)
- (4-Chloro-6-methoxyquinolin-3-yl)(p-tolyl)methanone (CAS 1351792-84-1)
- 2-Boc-6-chloro-3,4-dihydro-1H-isoquinoline-1-carboxylic acid (CAS 871730-33-5)
- 2-Chloro-3-(phenethylamino)naphthalene-1,4-dione (CAS 6307-22-8)
Recommended Standards
- 7-Chloro-8-methyl-2-(p-tolyl)quinoline-4-carboxylic acid (CAS 588712-25-8)
- 8-Chloro-2-(2,5-dimethylphenyl)quinoline-4-carboxylic acid (CAS 862647-94-7)
- 7-Chloro-8-methyl-2-(o-tolyl)quinoline-4-carboxylic acid (CAS 862647-91-4)
- 8-Chloro-2-(3,4-dimethylphenyl)quinoline-4-carboxylic acid (CAS 862647-95-8)
- 2-(5-Bromopyridin-2-yl)-2-cyanoacetic acid (CAS 1823925-39-8)
- 3,4-Dibromobenzenesulfonyl chloride (CAS 81903-80-2)
- Ethyl 2-(4-bromo-2-methylphenyl)thiazole-4-carboxylate (CAS 886368-25-8)
- 6-fluoro-7-nitro-1H-indazole (CAS 1279869-26-9)
- 5-Methyl-2-nitrothiophen-3-amine (CAS 1404364-31-3)
- 5-(Acetylamino)-1-phenyl-1H-pyrazole-4-carboxylic acid (CAS 51649-69-5)
- 5-amino-1-(pyridin-3-yl)-1H-imidazole-4-carboxamide (CAS 1798713-75-3)
- 4-((tert-Butyldiphenylsilyl)oxy)tetrahydrofuran-3-ol (CAS 2566779-25-5)
- Benastatin A (CAS 138968-85-1)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com