N-(4-ethoxyphenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamide CAS 433252-86-9
| CAS No. | 433252-86-9 |
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, N-(4-ethoxyphenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamide (C18H16F3N3O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 363.33 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
N-(4-ethoxyphenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamide (CAS 433252-86-9) is a high-purity analytical reference standard with the molecular formula C18H16F3N3O2 and a molecular weight of 363.33 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H16F3N3O2 |
| Molecular Weight | 363.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(2-ethoxyphenyl)-2-(2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)acetamide (CAS 478042-56-7)
- 2-((4-Ethoxyphenyl)amino)-N'-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide (CAS 326001-01-8)
- 2-((1-(2-Ethoxyphenyl)-1H-tetrazol-5-yl)thio)-N-(thiazol-2-yl)acetamide (CAS 874467-68-2)
- N-(4-Ethoxyphenyl)-1-(pyridin-4-yl)-3,4-dihydropyrrolo[1,2-a]pyrazine-2(1H)-carboxamide (CAS 899942-38-2)
- Ethyl 3-(3-((1-(4-ethoxyphenyl)-1H-tetrazol-5-yl)methyl)ureido)propanoate (CAS 1005293-30-0)
- 3-(4-Ethoxyphenyl)-5-(((2-fluorophenyl)sulfonyl)methyl)-1,2,4-oxadiazole (CAS 1326901-76-1)
- 3-(3-Ethoxyphenyl)-N'-(3-methoxybenzylidene)-1H-pyrazole-5-carbohydrazide (CAS 302917-94-8)
- 3-(2-Ethoxyphenyl)-2-(piperazin-1-ylmethyl)quinazolin-4(3H)-one (CAS 903499-49-0)
Recommended Standards
- n-(4-Methoxybenzyl)-2-(2-(trifluoromethyl)-1h-benzo[d]imidazol-1-yl)acetamide (CAS 478048-08-7)
- Ethyl 5-(4-ethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylate (CAS 938009-04-2)
- Mitomycin impurity 2 (CAS CATO-C4X-17012)
- Ethyl 2-((4-(4-fluorobenzyl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl)thio)acetate (CAS 294853-35-3)
- N-(3-methylbenzyl)oxetan-3-amine (CAS 1339184-51-8)
- 4-(2-Ethynylphenyl)thiazol-2-amine (CAS 2228369-57-9)
- tert-Butyl ((1S,4S,7S)-2-azabicyclo[2.2.1]heptan-7-yl)carbamate (CAS 1931962-94-5)
- 4-Chloro-1h-pyrazole-3-carbohydrazide (CAS 1005584-54-2)
- N-Benzyl-N,N-diethylethanaminium chloride hydrate (CAS 207124-62-7)
- 2-(2-Hydrazinylpyridin-4-yl)-4-phenylthiazole (CAS 1707727-53-4)
- H-Gly-Gly-βNA · HBr (CAS 3313-48-2)
- (S)-N-Ethyl-2-(pyrrolidin-3-yloxy)pyrimidin-4-amine hydrochloride (CAS 1417789-16-2)
- 1,3-Thiazinan-2-imine hydrochloride (CAS 2799-74-8)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com