2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione CAS 4338-50-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione.

2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione (CAS 4338-50-5) is a high-purity analytical reference standard with the molecular formula C5H5N3O3 and a molecular weight of 155.11 g/mol.

2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione (C5H5N3O3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Acetyl-1,2,4-triazine-3,5(2H,4H)-dione meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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