2,6-Difluoro-4-(hydroxymethyl)benzonitrile CAS 433939-89-0
| CAS No. | 433939-89-0 |
| Molecular Formula | C8H5F2NO |
| Molecular Weight | 169.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
2,6-Difluoro-4-(hydroxymethyl)benzonitrile (CAS 433939-89-0) is a high-purity analytical reference standard with the molecular formula C8H5F2NO and a molecular weight of 169.13 g/mol.
Structurally, 2,6-Difluoro-4-(hydroxymethyl)benzonitrile (C8H5F2NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 169.13 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 2,6-Difluoro-4-(hydroxymethyl)benzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5F2NO |
| Molecular Weight | 169.13 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Difluoro Standards
- 2,5-Difluoro-4-methoxybenzonitrile (CAS 1007605-44-8)
- 3,6-Difluoro-2-methoxybenzonitrile (CAS 1010413-52-1)
- 3,5-Difluoro-4-methoxybenzonitrile (CAS 104197-15-1)
- 5,6-Difluoro-2,3-dihydro-1H-isoindol-1-one (CAS 1192040-50-8)
- 2,6-Difluoro-4-hydrazinobenzonitrile (CAS 1211514-57-6)
- 2,6-Difluoro-4-methoxybenzonitrile (CAS 123843-66-3)
- 2,4-Difluoro-6-methoxybenzonitrile (CAS 1240518-41-5)
- 3,4-Difluoro-5-methoxybenzonitrile (CAS 1262552-14-6)
Recommended Standards
- 2,6-Difluoro-3-methoxybenzonitrile (CAS 886498-35-7)
- 2-Carboxy-5-methoxypyridine 1-oxide (CAS 672957-93-6)
- 2,5-Difluorobenzyl azide (CAS 622372-74-1)
- 2-Hydroxy-4-(hydroxyamino)benzoic acid (CAS 3096-66-0)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(2-hydroxyphenyl)butanoic acid (CAS 1260618-76-5)
- 2-t-Butyl-3-hydroxy-5-(trifluoromethyl)isoindolin-1-one (CAS 1242336-73-7)
- 1-[5-(3-fluorophenyl)-1,3,4-oxadiazol-2-yl]-6-azaspiro[2.5]octane (CAS 1354953-30-2)
- PP1 (CAS 172889-26-8)
- TRANS (+/-) 1-BENZYL-3-NITRO-4-PHENYLPYRROLIDINE (CAS 756791-42-1)
- 2-Hydroxy-4-(2-thienyl)pyrimidine (CAS 1269294-26-9)
- 10-(4-Bromophenyl)phenothiazine(contains 10% 10-(4-Iodophenyl)phenothiazine at maximum) (CAS 63524-03-8)
- 2-Amino-3-(2-fluoro-5-methyl-4-(trifluoromethyl)phenyl)propanoic acid (CAS 1435806-24-8)
- 6'-Bromospiro[cyclopropane-1,1'-inden]-3'(2'H)-one (CAS 1396777-69-7)
- Liraglutide Impurity 25 (CAS CATO-C4X-199225)
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