3-[(4,6-dimethylpyrimidin-2-yl)thio]-2-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}propanoic acid CAS 433952-67-1
| CAS No. | 433952-67-1 |
| Molecular Formula | C16H20N4O2S2 |
| Molecular Weight | 364.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-[(4,6-dimethylpyrimidin-2-yl)thio]-2-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}propanoic acid (CAS 433952-67-1) is a high-purity analytical reference standard with the molecular formula C16H20N4O2S2 and a molecular weight of 364.49 g/mol.
The molecular framework of 3-[(4,6-dimethylpyrimidin-2-yl)thio]-2-{[(4,6-dimethylpyrimidin-2-yl)thio]methyl}propanoic acid (C16H20N4O2S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H20N4O2S2 |
| Molecular Weight | 364.49 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
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Recommended Standards
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- 6,6'-(Hexane-1,6-diylbis(oxy))bis(2-methylquinolin-4-ol) (CAS 6305-68-6)
- (E)-N'-[(1Z)-2-Amino-1,2-dicyanoeth-1-en-1-yl]-N-(2,5-dimethoxyphenyl)methanimidamide (CAS 478050-17-8)
- tert-butyl (3R)-3-hydroxy-2,2-dimethyl-azetidine-1-carboxylate (CAS 2227199-03-1)
- Methyl 1-(2,4-dichlorophenyl)-4-hydroxy-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 121582-57-8)
- Phenyl-pyridazin-3-yl-methanone (CAS 60906-52-7)
- (3S,4R)-1-Boc-3-fluoropiperidin-4-ol (CAS 1174020-40-6)
- 4-Phenyl-5-((3-(trifluoromethyl)phenoxy)methyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 383145-60-6)
- 2-Chloro-6-methyl-1,4-diazine 2-chloro-6-methyl-pyrazine 2-chloro-6-methylpyrazine 38557-71-0 (CAS 38557-71-0)
- tert-butyl N-(2-aminocyclopropyl)carbamate (CAS 1395492-00-8)
- 6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine (CAS 1262888-28-7)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
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