1-(2,4-Bis(trifluoromethyl)phenyl)-2-bromoethan-1-one CAS 435271-21-9

Purity 97%+In StockPharmaceutical Standards
CAS No.435271-21-9
Molecular FormulaC10H5BrF6O
Molecular Weight335.04 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

1-(2,4-Bis(trifluoromethyl)phenyl)-2-bromoethan-1-one CAS 435271-21-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(2,4-Bis(trifluoromethyl)phenyl)-2-bromoethan-1-one.

1-(2,4-Bis(trifluoromethyl)phenyl)-2-bromoethan-1-one (CAS 435271-21-9) is a high-purity analytical reference standard with the molecular formula C10H5BrF6O and a molecular weight of 335.04 g/mol.

1-(2,4-Bis(trifluoromethyl)phenyl)-2-bromoethan-1-one (C10H5BrF6O) contains a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H5BrF6O
Molecular Weight335.04 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Br-containing

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