1-(4-Chlorobenzyl)piperazine hydrochloride CAS 435342-11-3
| CAS No. | 435342-11-3 |
| Molecular Formula | C11H15ClN2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-(4-Chlorobenzyl)piperazine hydrochloride is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-(4-Chlorobenzyl)piperazine hydrochloride (CAS 435342-11-3) is a high-purity analytical reference standard with the molecular formula C11H15ClN2HCl and a molecular weight of 247.16 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, 1-(4-Chlorobenzyl)piperazine hydrochloride is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 247.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15ClN2 HCl |
| Molecular Weight | 247.16 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorobenzyl Standards
- 1-(4-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-38-8)
- 1-(3-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001566-82-0)
- 1-(3-Chlorobenzyl)-1H-pyrazol-4-amine (CAS 1002033-41-1)
- 3-(2-Chlorobenzyl)pyrrolidine (CAS 1003561-98-5)
- 1-(3-Chlorobenzyl)-4-isothiocyanato-1h-pyrazole (CAS 1004193-35-4)
- 1-(3-Chlorobenzyl)-5-methyl-1,2-dihydro-3h-pyrazol-3-imine (CAS 1004643-48-4)
- 1-(4-Chlorobenzyl)-2-oxo-N-(3-phenylpropyl)-1,2-dihydro-1,8-naphthyridine-3-carboxamide (CAS 1005291-55-3)
- 1-(2-Chlorobenzyl)-5-methyl-3,4-dinitro-1h-pyrazole (CAS 1005669-24-8)
Recommended Standards
- (5-Bromo-2-hydroxy-4-methoxyphenyl)(phenyl)methanone (CAS 3286-93-9)
- N-((6-bromopyridin-3-yl)methyl)-2-methoxy-N-methylethan-1-amine (CAS 2568131-01-9)
- 1-(4-(5-(1-Hydroxyethyl)-3-methylpyridin-2-yl)piperazin-1-yl)ethanone (CAS 1355203-76-7)
- 1-(Piperidin-3-yl)piperidin-2-one (CAS 933715-12-9)
- N-(4-bromophenyl)-4-nitrobenzamide (CAS 59280-03-4)
- 1-(6-(4-Acetylpiperazin-1-yl)pyridin-3-yl)propan-1-one (CAS 1355224-82-6)
- 6-Chlorovanillin (CAS 18268-76-3)
- 5-(4-(Trifluoromethoxy)phenoxy)picolinaldehyde (CAS 1686102-88-4)
- [2-(pyridin-2-yl)ethyl]urea (CAS 20273-53-4)
- Semaglutide impurity 75 (CAS CATO-C4X-222675)
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