3-(6-Methyl-quinazolin-4-ylamino)-propionic acidhydrochloride CAS 435345-11-2
| CAS No. | 435345-11-2 |
| Molecular Formula | C12H13N3O2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-(6-Methyl-quinazolin-4-ylamino)-propionic acidhydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-(6-Methyl-quinazolin-4-ylamino)-propionic acidhydrochloride (CAS 435345-11-2), a certified reference material (molecular formula C12H13N3O2HCl, MW 267.71 g/mol) for analytical method development and quality control.
3-(6-Methyl-quinazolin-4-ylamino)-propionic acidhydrochloride (C12H13N3O2HCl) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H13N3O2 HCl |
| Molecular Weight | 267.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Methyl Standards
- 1-(Quinazolin-4-yl)pyrrolidine-2-carboxylic acid (CAS 1008675-45-3)
- Quinazolin-8-amine (CAS 101421-74-3)
- N1-(Quinazolin-4-yl)propane-1,3-diamine (CAS 1016-23-5)
- 1-(Quinazolin-2-yl)guanidine (CAS 102331-12-4)
- N-Quinazolin-4-ylalanine hydrochloride (CAS 1030264-64-2)
- 2-(Quinazolin-4-ylamino)-butyric acidhydrochloride (CAS 1030280-69-3)
- Quinazolin-7-ylmethanamine (CAS 1083299-31-3)
- Quinazolin-8-ylmethanamine (CAS 1083368-42-6)
Recommended Standards
- n-((3-Ethyl-1-methyl-1h-1,2,4-triazol-5-yl)methyl)cyclopentanamine (CAS 1342042-39-0)
- (5-Methyl-1-phenyl-1H-pyrazole-4-yl)methanamine (CAS 894779-67-0)
- (2R,4R)-1-Benzyl 2-ethyl 4-(tosyloxy)pyrrolidine-1,2-dicarboxylate (CAS 130830-60-3)
- 2-[4-(cyclohexylamino)phenyl]acetonitrile (CAS 1157685-94-3)
- 2-((2-Chloro-6-fluorobenzyl)(cyclopropyl)amino)ethanol (CAS 1249235-18-4)
- 3-Fluoro-4-methylbenzenethiol (CAS 64359-35-9)
- 3,3'-Dimethoxy-(1,1'-biphenyl)-4,4'-diamine dihydrochloride (CAS 20325-40-0)
- 2-(3-Chloro-4-nitrophenyl)-4-phenylcyclohexan-1-one (CAS 1980086-54-1)
- (±)-Dinotefuran-d3 (CAS CATO-CCPD101783)
- Semaglutide impurity 273 (CAS CATO-C4X-2226273)
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