2-Chloro-6,8-dimethylquinoline-3-carboxylic acid CAS 436087-26-2
| CAS No. | 436087-26-2 |
| Molecular Formula | C12H10ClNO2 |
| Molecular Weight | 235.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-6,8-dimethylquinoline-3-carboxylic acid is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-6,8-dimethylquinoline-3-carboxylic acid (CAS 436087-26-2), a certified reference material (molecular formula C12H10ClNO2, MW 235.67 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-6,8-dimethylquinoline-3-carboxylic acid (C12H10ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-Chloro-6,8-dimethylquinoline-3-carboxylic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10ClNO2 |
| Molecular Weight | 235.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 1-(2-Chloro-7-methoxyquinolin-3-yl)ethanone (CAS 1017463-80-7)
- Methyl 4-chloro-8-methylquinoline-2-carboxylate (CAS 1020101-33-0)
- 2-Chloro-1-(2,3-dihydro-1H-benzo[d]imidazo[1,2-a]imidazol-1-yl)ethan-1-one (CAS 1030421-66-9)
- 6-Chloro-3-methyl-3,5-dihydroimidazo[2,1-b]quinazolin-2(1H)-one (CAS 105622-85-3)
- 5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxamide (CAS 117518-83-9)
- 2-Chloro-N-(5'-hydroxynaphthalen-1'-yl)-acetamide (CAS 118639-06-8)
- 5-Chloro-3-(2,4-dimethylphenyl)-1,2-oxazole-4-carbaldehyde (CAS 1188029-06-2)
- 6-Chloro-N4-(pyridin-4-ylmethyl)pyrimidine-4,5-diamine (CAS 1192975-97-5)
Recommended Standards
- 2-Chloro-6-(4-oxopiperidin-1-yl)isonicotinonitrile (CAS 848499-11-6)
- 2-Chloro-6,8-dimethylquinoline-4-carboxylic acid (CAS 50503-78-1)
- 2-Chloro-6-(1-cyanocyclobutyl)benzoic acid (CAS 2053644-30-5)
- 2-Chloro-7,8-dimethylquinoline-3-carboxylic acid (CAS 338428-51-6)
- 3-(3-Bromophenyl)-4,5-diphenyl-4H-1,2,4-triazole (CAS 1388231-53-5)
- 4-(sec-Butoxy)-N-(4-butoxybenzyl)aniline (CAS 1040685-33-3)
- 6-Chloro-8-methoxyquinolin-4(1H)-one (CAS 1189107-30-9)
- 2-(3-Bromo-2,2-dimethylpropoxy)butane (CAS 1489663-65-1)
- 4-Chloro-N-(pyridin-4-ylmethyl)aniline (CAS 29083-47-4)
- Fondaparinux Sodium Impurity 13 (CAS CATO-C4X-205213)
- Nitrendipine impurity 22 (CAS 89267-43-6)
- 5-[(pyrrolidin-1-yl)methyl]pyridin-2-amine (CAS 913573-02-1)
- 3,5-Bis(trifluoromethyl)bromobenzene (CAS 328-70-1)
- Insulin Degludec Impurity 13 (CAS CATO-C4X-215713)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com